Title
Synthesis and physicochemical study of gum arabic sulfates
Authors
ALEKSANDR S. KAZACHENKO, FERIDE AKMAN, UTKIRJON HOLIKULOV, YAROSLAVA BEREZHNAYA, NOUREDDINE ISSAOUI, ANNA S. KAZACHENKO, OMAR M. AL-DOSSARY, OLGA FETISOVA, SVETLANA NOVIKOVA and TIMUR IVANENKO

Received May 19, 2024
Published Volume 59 Issue 1-2 January-February
Keywords gum arabic, sulfamic acid, physicochemical characteristics, DFT

Abstract
Polysaccharide sulfates have many valuable types of biological activity, such as anticoagulant, hypolipidemic, antithrombotic, etc. The biological activity of sulfated polysaccharides depends on various physicochemical characteristics. In this work, the synthesis and physicochemical characteristics of gum arabic sulfates were studied. Sulfation of gum arabic was carried out with sulfamic acid in the presence of urea with varying ratios of the sulfating complex. The influence of process duration and temperature on the sulfur content in gum arabic sulfates was assessed. The original and sulfated gum arabic was studied using a complex of physicochemical methods: FTIR, XRD, thermal and elemental analysis and DFT. The introduction of a sulfate group into the gum arabic macromolecule was proven by FTIR spectroscopy by the appearance of corresponding absorption bands. According to thermal analysis, during the sulfation process, the thermal stability of gum arabic decreases due to the formation of low-stable sulfuric acid ester groups.