Title
A review of orodispersible films for enhanced drug delivery
Authors
ABRAR HUSSAIN and ZULCAIF AHMAD

Received August 9, 2024
Published Volume 59 Issue 1-2 January-February
Keywords orodispersible films, drug delivery, patient compliance, rapid disintegration, mucoadhesion

Abstract
This review article provides a comprehensive overview of orodispersible films as a versatile drug delivery system. Orodispersible films, also known as buccal films, offer several advantages over traditional oral dosage forms, particularly for patients who have difficulty swallowing, such as children, the elderly, and those with dysphagia. These films rapidly disintegrate in the oral cavity, allowing for easy administration and improved patient compliance. The review discusses the types of buccal films, including flash release, mucoadhesive melt-away, and mucoadhesive sustained-release films, as well as the key factors influencing their development and performance. It also highlights the various drugs that are suitable candidates for inclusion into orodispersible films, including those with low bioavailability, first-pass metabolism, and local effects. The review emphasizes the growing interest in this technology and its potential for addressing the challenges associated with traditional oral drug delivery.